ITGA1 human: integrin, alpha 1

Aliases: laminin and collagen receptor, integrin, alpha 1, very late activation protein 1, VLA1, ITGA1, CD49a

Pfam Domain Structure

From ITGA1 (human)

Protein Overview
Official Gene Name ITGA1 (H. sapiens)
RefSeq Protein Name integrin, alpha 1
UniProt Gene Symbol ITA1_HUMAN
UniProt Name Integrin alpha-1
Entrez Gene Summary This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq]
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Consortium Results & Data
Proteomics» Table 1. Identification and Quantitation of Proteins from Cell Body (CB) and Pseudopodium (PD) fractions
IPI Locus Description CB Spectra CB peptide PD Spectra PD peptide ratio
IPI00106698 ITGA1 PELOTA HOMOLOG. 2 2 5 5 2.50
Proteomics» Table 2. Proteins in major organelles and subcellular compartments
IPI Locus Description CB Spectra PD Spectra ratio Location
Isoform Name RefSeq Protein RefSeq mRNA Swissprot ID
NP_852478 NM_181501 P56199

bold indicates the primary isoform


How many degrees of interaction?

Legend: Legend for CMKB pathways